Holmes of Baker Street' by Bill Barry appeared in 1976-1977. A short-lived half-page Sherlock Holmes comic strip appeared daily and Sunday in the 1950s, written by radio scriptwriter Edith Meiser and drawn by Frank Giacoia.

Sherlock Holmes was drawn by Leo O'Mealia (who later drew covers for Action Comics) and distributed by the Bell Syndicate. The first, titled Sherlock Holmes, ran from 1930 to 1931. Three Sherlock Holmes adaptations have appeared in American newspapers. Card games based on Sherlock Holmes include I Say, Holmes! (2007, updated 2014), Holmes: Sherlock & Mycroft (Devir Games, 2015), and Clash of Minds: Holmes vs Moriarty (2019). Other Sherlock Holmes board games include Watson & Holmes (Ludonova, 2015), Beyond Baker Street (Z-Man Games, 2016), and Sherlock Holmes and Moriarty's Web (2016). The board game A Study in Emerald, released in 2013, was based on the Sherlock Holmes pastiche ' A Study in Emerald' by Neil Gaiman. Multiple expansions have since been published for both games.

The board game 221B Baker Street ( Gibsons Games) was first developed in 1975, and the book-based game Sherlock Holmes: Consulting Detective (Sleuth Publications) was published in 1981. They include the original writings, 'together with the translations of these tales into sixty-three languages, plus Braille and shorthand, the writings about the Writings or higher criticism, writings about Sherlockians and their societies, memorials and memorabilia, games, puzzles and quizzes, phonograph records, audio and video tapes, compact discs, laser discs, ballets, films, musicals, operettas, oratorios, plays, radio and television programs, parodies and pastiches, children's books, cartoons, comics, and a multitude of other items - from advertisements to wine - that have accumulated throughout the world on the two most famous characters in literature.' Board games De Waal lists over 25,000 Holmes-related productions and products. The four volumes of the Universal Sherlock Holmes (1995) compiled by Ronald B. The stories of Sherlock Holmes by Sir Arthur Conan Doyle have been very popular as adaptations for the stage, and later film, and still later television. See also: Popular culture references to Sherlock Holmes

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